Immunology

The vaccine race

With more than 150 COVID-19 vaccines in development, we put the three front-runners under the microscope and look at the incredible, unprecedented development work of the last year.

Smallpox, salmonella and sacrifice

Stephen Mortlock looks back at the history of the Aztec civilisation, the diseases that struck and the treatments that were created.

Urgent need for early COVID-19 treatments

COVID-19 treatments for people with early infection are needed urgently, according to Anthony S Fauci, Director of the US National Institute of Allergy and Infectious Diseases.

What is long COVID?

Dr David Strain, a Senior Clinical Lecturer, is heading up the British Medical Association’s work on the long-term impact of COVID-19. Here he explains what we know so far about long COVID.

New biomarker to prevent graft-versus-host disease

A recent report sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD).

Air pollution and COVID-19

Scientists have found that long-term exposure to urban air pollution may have made COVID-19 more deadly.

COVID-19 not characterised by a cytokine storm

Inflammatory proteins known as cytokines play a crucial role in the immune response. If this response is too strong – a phenomenon known as “cytokine storm” – it can cause harm to the patient.

One-to-one: COVID response controvery

We hear from Professor Sunetra Gupta – the theoretical epidemiologist who believes in herd immunity and doesn’t believe in the lockdown.

"Three times risk for frontline healthcare workers"

Frontline healthcare workers with adequate personal protective equipment (PPE) have a three-fold increased risk of a positive SARS-CoV-2 test, compared with the public.

Screening to improve mAb-based drugs

By screening potential monoclonal antibody (mAb)-based drugs solely on a measure of their colloidal stability, scientists may be able to weed out mAbs that do not respond efficiently in solution early in the drug discovery process, according to a new study.

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