Molecular Pathology & Genomics

New approach for ovarian cancer treatment?

Immune checkpoint inhibitors are a type of cancer treatment that help the immune system’s T cells recognise and attack tumours. But these immunotherapy drugs aren’t effective against all cancers.

Potential vaccine and treatment for alzheimer’s

A promising new approach to potentially treat Alzheimer’s disease – and also vaccinate against it – has been developed by a team of UK and German scientists.

Genomic medicine: breaking new ground

Cancer Genomics Project Manager Deborah Lakeland describes the cultural change sweeping across healthcare provision in the UK and its importance in clinical laboratories.

Shining a light ...on lighthouse laboratories

We look back over the history of the lighthouse labs and whether better quality control and tighter regulation are needed.

An immersive experience: cancer exhibition at the Crick

The Francis Crick Institute has opened Outwitting Cancer – Making Sense of Nature’s Enigma, an immersive exhibition and the first to take place within a working science laboratory, home to cancer scientists from across the world. Here, Exhibitions Manager Hana Dethlefsen talks through the launch.

Tech news: October

This month's top tech news stories

Under the microscope: chronic allograft dysfunction

What is chronic allograft dysfunction (CLAD)?

A range of pathologies that cause a transplanted lung to not achieve or maintain normal function. CLAD manifests as airflow restriction or obstruction.

Evolutionary changes in brain development

More than 3000 regions in the human genome are very different to those in the genome of any other mammals, including our closest primate relatives.

Turning normal cells into cancer cells

There is new evidence that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

One fat cell subtype responds to insulin stimulation

Scientists have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these – AdipoPLIN – that responds to insulin.

Urine test to detect brain tumours

MicroRNAs in urine could be a promising biomarker to diagnose brain tumours and regular urine tests could help early detection and treatment, it is claimed.

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