Molecular Pathology & Genomics

DNA biosensor for low-cost diagnostics

A new biosensor chip that boasts an accurate and inexpensive design may increase accessibility to high-quality diagnostics, it is claimed. 

Diagnostic potential of amniotic fluid cells

A clinical research team from the University of Hong Kong is behind the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA sequencing in prenatal diagnosis.

CRISPR and developing diagnostics

In a first for the genetic toolset CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA and single- and double-stranded DNA.

Beyond CRISPR-Cas9

We hear from Jonathan Gootenberg and Omar Abudayyeh – scientists who are developing a new tool to extend the frontiers of gene therapy.

Relevance, importance and requirement: Diploma of Expert Practice in Ultrastructural Pathology

Tracey de Haro, Specialist Scientific Lead for Electron Microscopy, University Hospitals of Leicester, looks at the revamped qualification.

Rogue immune cells linked to leukaemia

Gene variants associated with leukaemia can produce “rogue” immune cells that drive autoimmune diseases, according to a new study.

Artificial enzymes programmed to destroy SARS-CoV-2

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus.

Education, development and knowledge acquisition

It’s not about winning, it’s about the journey and what we learn along the path of that journey that really matters, writes Dr Guy Orchard.

Biopsy, diagnostics and tumour removal

Researchers from Japan may have devised a way to perform the initial biopsy, lab tests, and subsequent tumour removal during one surgical procedure.

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