Molecular Pathology & Genomics

Artificial enzymes programmed to destroy SARS-CoV-2

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus.

Education, development and knowledge acquisition

It’s not about winning, it’s about the journey and what we learn along the path of that journey that really matters, writes Dr Guy Orchard.

Biopsy, diagnostics and tumour removal

Researchers from Japan may have devised a way to perform the initial biopsy, lab tests, and subsequent tumour removal during one surgical procedure.

Cell-free DNA cancer detection

A US-led research team has reported successful results from an experimental cell-free DNA (cfDNA) cancer-detection system that is claimed to be cost effective.

Recent advances in biomedical science

Deputy Editor Andrew Blann summarises some articles recently published in the British Journal of Biomedical Science.

Car t-cell therapy

The immunotherapy tool that ushered in a new era in cancer treatment options.

Genetic method for identifying hundreds of disease agents

A new paper compares the pathogen-detecting ability of a next-generation sequencing (NGS) system — the Respiratory Pathogen Infectious Diseases/Antimicrobial Resistance Panel (RPIP) — with a previously studied NGS system and standard of care (SOC) diagnostic methods for samples obtained with bronchoalveolar lavage.

“Gene editing via CRISPR/cas9 can lead to cell toxicity and genome instability”

CRISPR/Cas9 is a commonly used, very precise, gene editing technique often known as “genetic scissors”.

AI and ecg heart trace to predict diabetes

An artificial intelligence (AI) algorithm, derived from the features of individual heartbeats recorded on an ECG (electrocardiogram), can accurately predict diabetes and pre-diabetes, suggests preliminary research.

An electrophoresis case study

Madihah Abbas, Specialist Biochemistry Team Manager at Christie Pathology Partnership, looks at result interpretation, comparing gel and capillary zone electrophoresis.

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