Molecular Pathology & Genomics

Molecule to remodel microbiome

Scientists at Scripps Research claim they have developed molecules that can remodel the bacterial population of intestines to a healthier state.

Detecting motor neurone disease

Scientists have identified a potential pattern within blood that signals the presence of motor neurone disease.

Improving drug delivery

A group of US scientists has developed a new way to deliver molecules that target specific genes within cells.

Under the microscope: The G protein-coupled estrogen receptor

Tell me about this receptor
The G protein-coupled estrogen receptor (let’s call it the GPER) is a seven-transmembrane-domain receptor that mediates non-genomic estrogen-related signalling.

Map of mutations

Research from UCL has identified almost 200 changes to the COVID-19 genome, each one a clue to revealing the history of the virus and possibly its future.

More effective stem cell transplant

Scientists have developed a new way to make blood stem cells present in the umbilical cord “more transplantable”.

Curative treatment for heart disease

Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn.

New antibiotic resistance gene

Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria.

Crumpled graphene for cancer detection

Graphene-based biosensors could usher in an era of liquid biopsy for detecting DNA cancer markers circulating in a patient’s blood or serum.

New genetic cell insights

Researchers have developed the first computational model of a human cell and simulated its behaviour for 15 minutes.

Giant cavity discovered in TB molecule

Scientists have discovered a strange new feature of a protein that is thought to be important in the development of tuberculosis.