Molecular Pathology & Genomics

Improving drug delivery

A group of US scientists has developed a new way to deliver molecules that target specific genes within cells.

Under the microscope: The G protein-coupled estrogen receptor

Tell me about this receptor
The G protein-coupled estrogen receptor (let’s call it the GPER) is a seven-transmembrane-domain receptor that mediates non-genomic estrogen-related signalling.

Map of mutations

Research from UCL has identified almost 200 changes to the COVID-19 genome, each one a clue to revealing the history of the virus and possibly its future.

More effective stem cell transplant

Scientists have developed a new way to make blood stem cells present in the umbilical cord “more transplantable”.

Curative treatment for heart disease

Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn.

New antibiotic resistance gene

Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria.

Crumpled graphene for cancer detection

Graphene-based biosensors could usher in an era of liquid biopsy for detecting DNA cancer markers circulating in a patient’s blood or serum.

Advancing genomics

Genetic discoveries over the past 25 years have substantially advanced understanding of both rare and common diseases, it is reported.

Rare genetic mutations in donor stem cells

A stem cell transplant is a common treatment for blood cancers, such as acute myeloid leukemia (AML).

British Journal of Biomedical Science: issue 1 2020 – a synopsis

Deputy Editor Tony Rhodes provides a brief glimpse of the articles on offer in the first issue of 2020.

Pulling the plug on pancreatic cancer

UK scientists have identified a new way to kill pancreatic cancer cells by “pulling the plug” on the energy generator that fuels calcium pumps on their cell surface.

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