Clinical Chemistry

Incident.Response.Outcome.

Dervilla Gorman and Naomi DeJager describe their roles as bronze commanders at Viapath Analytics and discuss their responses to incidents that have affected pathology services. 

My lab: remote and rural healthcare

Chloe Clapham, Clinical Laboratories Quality Manager at Balfour Hospital, gives a guided tour of her Orkney lab.

The Lewis Blood Group System and Secretor Status

Malcolm Needs CSci FIBMS, formerly of the NHSBT, delves into the history and science of a notable blood group system.

Raised serum ferritin

Honorary senior lecturer and consultant haematologist Dr Farooq A Wandroo and his colleagues ask, what is the clinical significance of a markedly elevated serum ferritin?

Blood test for Alzheimer’s

Investigators at Brigham and Women’s Hospital in the US are working to develop a blood test that could accurately diagnose or even predict Alzheimer’s disease before symptoms appear.

Clinical chemistry classics: tumour markers

This series on tumour markers concludes with a review of pioneering work in the development, analysis and clinical application of an important serum tumour marker – prostate specific antigen.

Non-invasive blood glucose test

A promising evaluation has been published on new technology to monitor blood glucose levels without needles or a finger prick.

Journal-based learning exercises - November 2018

Each article’s contents should be read, researched and understood, and you should then come to a decision on each question. The pass mark is 17 out of 20 questions answered correctly. JBL exercises may be completed at any time until the published deadline date. Please select your choice of correct answers and complete the exercises online at: www.ibms.org/cpd/jbl

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Clinical chemistry classics: tumour markers

The series on tumour markers continues with a brief review of pioneering work in the development, analysis and clinical application of an important serum tumour marker- CA19-9.

Liquid biopsy and mathematical modelling

An evolutionary model utilising serial blood samples from patients with advanced colorectal cancer treated with anti-EGFR therapies in a phase II trial could predict personalised waiting time for progression.

How to…ensure correct calibration

Specialist Biomedical Scientist Dan Kelly looks into linear calibration curves, Beer-Lambert’s law and IQC interpretation.

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