Molecular Pathology & Genomics

Beyond SARS-COV-2

Dr Jennifer Cane, a Postdoctoral Research Assistant, asks what sequencing respiratory viruses can tell us.

Microsatellite instability cancer tests

New US research compares the data of newly diagnosed cancer patients who received two different types of tests to determine their course of treatment.

Novel genetic variants associated with Alzheimer’s disease

New research has identified several genetic variants that may influence Alzheimer’s disease risk, putting researchers one step closer to uncovering biological pathways to target for future treatment and prevention.

Bat swarming and immunity

Bats carry some of the deadliest zoonotic diseases that can infect both humans and animals, such as Ebola and COVID-19.

Fibroblast cells and pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, it is claimed.

Pores for thought

A team from Nottingham looks at intraoperative molecular diagnosis of brain tumours using nanopore sequencing.

Activating genes using CRISPR technology

There are over 7000 different rare genetic diseases, and often it can be a significant challenge and take a long time to receive a correct diagnosis.

Nanofluidic device that can capture single proteins

Researchers have developed an innovative nanofluidic device capable of capturing single proteins stochastically and detecting them digitally at their naturally high concentrations. This breakthrough could potentially lay the foundation for the future of personalised disease prevention and treatment.

Mitochondrial DNA biomarkers

In an eight-year study of more than 600 older adults, US researchers say they have further linked levels of cell-free DNA circulating in the blood to chronic inflammation and frailty.

Testing cancer drugs in space

Scientists at University of California San Diego Sanford Stem Cell Institute launched several new nanobioreactor experiments onto the International Space Station.

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