Molecular Pathology & Genomics

Tech news: October

This month's top tech news stories

Under the microscope: chronic allograft dysfunction

What is chronic allograft dysfunction (CLAD)?

A range of pathologies that cause a transplanted lung to not achieve or maintain normal function. CLAD manifests as airflow restriction or obstruction.

Evolutionary changes in brain development

More than 3000 regions in the human genome are very different to those in the genome of any other mammals, including our closest primate relatives.

Turning normal cells into cancer cells

There is new evidence that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

One fat cell subtype responds to insulin stimulation

Scientists have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these – AdipoPLIN – that responds to insulin.

Urine test to detect brain tumours

MicroRNAs in urine could be a promising biomarker to diagnose brain tumours and regular urine tests could help early detection and treatment, it is claimed.

Diagnose crohn’s with an engineered organism

Researchers have engineered a bacterium with the necessary capabilities for diagnosing a human disease.

Genetic risk factor for stroke

Researchers have identified a common genetic variant as a risk factor for stroke – especially in patients older than 65.

Precision genomics in cancer treatments

Scientists have identified genomic signatures in women developing the most common type of breast cancer that can be associated with long-term survival.

Diagnosis of Liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

Prostate cancer genetics study shows disparities

Risk of prostate cancer is about 75% higher, and more than twice as deadly, in men of African ancestry compared with men of European ancestry.

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