A randomised controlled trial found that colonoscopy assisted by computer-aided detection (CAD) was not associated with improved detection of advanced colorectal neoplasias.

More than 3000 persons with a positive faecal immunochemical test (FIT) were randomly assigned to colonoscopy with or without CAD to evaluate the contribution of CAD to colonoscopic detection of advanced colorectal neoplasias, adenomas, serrated polyps, and non-polypoid and right-sided lesions.
The researchers found no significant difference in advanced colorectal neoplasia detection rate or the mean number of advanced colorectal neoplasias detected per colonoscopy between the two groups.
These findings suggest the need for additional research and more defined detection parameters in CAD.
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