Immunology

Gut bacteria drive autoimmune disease

Bacteria found in the small intestines of mice and humans can travel to other organs and trigger an autoimmune response, states a new paper.

24/7 laboratory service

With round-the-clock working becoming the norm in the NHS, Training Officer Chika K Eze looks at its potential impact for pathology departments.

Preventing allergic reactions

Researchers have discovered a new mechanism in which an antibody can prevent allergic reactions in a broad range of patients.

No antibiotics for sore throats

Doctors should not prescribe antibiotics for most people with sore throats, say new guidelines. While most sore throats are caused by viral infections, research suggests antibiotics are prescribed in 60% of cases.

The enzyme that defines colon cancer

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells. It appears to drive the conversion of normal tissue into cancer by attaching sugar molecules, or glycans, to proteins in the cell.

Repurposed Zika drug

A drug used to treat hepatitis C effectively protected and rescued neural cells infected by the Zika virus. The results were consistent across cell cultures and mouse models. It also blocked transmission of the virus to mouse foetuses, the research found.

Bacteria and immune responses

Genetic differences between different strains of the same pathogenic bacterial species appear to result in widely varying immune system responses, it is reported.

Hubs install POCT analysers

Thame and Marlow Community Hubs, within Buckinghamshire Healthcare NHS Trust, have each recently installed HORIBA Medical’s latest point-of-care testing analyser, the Microsemi CRP.

March Journal-based learning

Each article’s contents should be read, researched and understood, and you should then come to a decision on each question. The pass mark is 17 out of 20 questions answered correctly. JBL exercises may be completed at any time until the published deadline date. Please select your choice of correct answers and complete the exercises online at: www.ibms.org/cpd/jbl

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