News

AddToAny

Google+ Facebook Twitter Twitter

Creating human bone marrow tissue

Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time.

Bone Marrow Matrix

For years researchers have been trying to reproduce bone marrow in the lab to better understand the mechanisms of blood formation and to develop new therapies.

However, this has proven extremely difficult as in conventional in vitro models, blood stem cells lose their ability to multiply and differentiate into different types of blood cells.

Now, researchers have engineered artificial bone marrow niche in which the stem and progenitor cells are able to multiply for a period of several days. It combines human mesenchymal stromal cells with a porous, bone-like 3-D scaffold and mimics the complex biological properties of natural bone marrow niches.

bit.ly/BS_JulyNews02

Related Articles

"Mind-boggling" conversion to neurons

Human immune cells in blood can be converted directly into functional neurons in the laboratory in about three weeks, say scientists.

Growing brains

Growing brains

They may only be small collections of cells at present, but neurological surgeon Ben Waldau believes that brain organoids could have a big impact in the future.

100,000 Genomes Project hits halfway

100,000 Genomes Project hits halfway

Genomics England has passed the halfway point in its mission to sequence 100,000 genomes.

Top