Google+ Facebook Twitter Twitter

Secondary malignancy: a case study

Healthcare Science Section Lead Michelle Bolam presents a case study in which a patient with chronic lymphocytic leukaemia was later diagnosed with chronic myeloid leukaemia.

Routine monitoring bloods were received into the laboratory from Haematology Outpatients on a 73-year-old female with a clinical history of a chronic lymphocytic leukaemia (CLL), diagnosis in 1999. The patient underwent chemotherapy for this in 2019 in the form of chorambucil and obinutuzumab to control the CLL, which was in remission.

When comparing the patient’s full blood count (FBC) on this occasion to their previous sample four months prior there was a marked difference (results shown in Table 1). The patient now appeared to have a leucocytosis and a thrombocytosis, which did not match with the patient’s clinical history of CLL. A peripheral blood film was made in order to investigate the many abnormal parameters to ensure the analyser was giving accurate results.

Click here to read the full article

Image credit | Shutterstock

Related Articles

Genes identified to potentially diagnose Lyme disease

Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified 35 genes that are particularly highly expressed in people with long-term Lyme disease.

The HSD developing specialist skills

Specialist Biomedical Scientist Naveed Sadia outlines her preparations for the Higher Specialist Diploma and her hopes for how it will benefit her career.

My lab: specialist testing services

Phil Cummings, Training Manager, and Herbert Tsuro, Project Lead, give a guided tour of blood transfusion laboratories in Leeds.

Three placements

Elesha George, a fourth-year student at Aberdeen’s Robert Gordon University, talks through a year of very different placements.