Genetic discoveries over the past 25 years have substantially advanced understanding of both rare and common diseases, it is reported.
This has furthered the development of treatment and prevention for ailments ranging from inflammatory bowel diseases to diabetes.
This is outlined in a new paper entitled “A brief history of human disease genetics”.
It reviews breakthroughs in the association of specific genes with particular disorders, progress mostly driven by advances in technology and analytical approaches. The study also provides a framework for medical innovation to improve clinical care in the field.
The researchers say the biggest task in the coming decade will be to optimise and broadly implement strategies that use human genetics to enhance understanding of health and disease, and maximise the benefits of treatment.
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