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Tackling oral infections

Nearly two-thirds of the denture-wearing population suffer frequent fungal infections that cause inflammation, redness and swelling in the mouth.

To treat denture-related stomatitis, researchers have turned to 3D printers to build dentures filled with microscopic capsules that periodically release amphotericin B, an antifungal medication.

The results of new research show the drug-filled dentures can reduce fungal growth.

Unlike current treatment options – such as antiseptic mouthwashes – the new development can also help prevent infection while the dentures are in use.

Applications from this research could be applied to various other clinical therapies, including splints, stents, casts and prostheses, according to those behind the research team.

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